Treatment Comparison9 min read

Spravato vs TMS: Comparing Two Modern Depression Treatments

Compare Spravato (esketamine) and TMS (transcranial magnetic stimulation) for depression. Learn the differences in how they work, time commitment, and results.

Next Step Psychiatry|Updated January 24, 2025

Spravato vs TMS: Which Depression Treatment Is Right for You?

If traditional antidepressants haven't worked, you've likely researched both Spravato and TMS. The team at Next Step Psychiatry can help you understand your options.

Quick Comparison

FactorSpravatoTMS
How it worksNasal spray (medication)Magnetic pulses to brain
Time to see resultsDays to weeks4-6 weeks
Session length2+ hours20-40 minutes

How Spravato Works

Spravato (esketamine) is a nasal spray that:

  • Targets glutamate/NMDA receptors
  • Promotes rapid neural connections
  • Shows effects within hours to days

How TMS Works

TMS uses magnetic fields to:

  • Stimulate nerve cells
  • Target mood regulation areas
  • Gradually "reset" brain activity

Choosing Between Them

Consider Spravato if:

  • You need rapid relief
  • Your schedule allows 2+ hour appointments
  • You can arrange rides home

Our Recommendation

At Next Step Psychiatry, we offer Spravato because:

Making Your Decision

We're happy to discuss both options. Call (678) 437-1659 to learn which treatment might be best. Meet our experienced providers at Next Step Psychiatry.

Related Topics

spravato vs tmstms vs spravatotms or esketaminedepression treatment comparison

Ready to Explore Spravato Treatment?

If you're struggling with treatment-resistant depression, Spravato could be the breakthrough you've been waiting for. Contact Next Step Psychiatry in Atlanta for a consultation.